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Genetics Research Specialist

Hiring Organization:
Wisconsin National Primate Research Center

Date Posted:

Position Description:
A position is available in the Wisconsin National Primate Resesarch Center (WNPRC) Genetics Services Unit overseen by Dr. David O'Connor at the AIDS Vaccine Research Laboratory. Genetics Services is a research service unit that specializes in fee-for-service high-throughput genotyping of immune loci in nonhuman primates (NHP). Understanding NHP genetics is essential for unlocking the secrets of AIDS immunity, organ transplant tolerance, and susceptibility to infectious disease. The applicant will provide technical assistance to help design experiments and develop improved technologies for understanding the relationship between genetics and disease, while working with other laboratories that provide NHP samples for advanced analyses available only through Genetics Services.

Job Duties:

Duties include but are not limited to the following:
-High-throughput isolation of nucleic acids and preparation of templates for DNA sequencing .
-Operate deep DNA sequencing instruments including an Illumina MiSeq and PacBio Sequel .
-Analyze large deep DNA sequencing datasets for Major Histocompatibility Complex (MHC) genotyping as well as additional immunologically important genomic regions such as TRIM5, killer immunoglobulin-like receptors (KIR), and Fc gamma receptors (FCGR) .
-Prepare genotyping reports and presentations .
-Evaluate new technology platforms for MHC allele discovery and genotyping .
-Assist with the development and evaluate new methods for analyzing and curating sequence data for immune gene families such as MHC, TRIM5, KIR and FCGR .
-Assist with administrative components such as purchasing, budget preparation, and project logistics .

The successful applicant will also be expected to work with Dr. O'Connor on other projects within his laboratory as time permits.

More information about the Genetics Services Unit and Dr. O'Connor's research program can be found at: and

For full job posting and to apply online, please go to:

Degree and Area of Specialization:
Bachelor's degree in biological sciences, preferrably genetics, biology, microbiology, immunology, or related field.

Relevant Work Experience:
Coursework in a molecular biology or related discipline required. Undergraduate experience in a biomedical research laboratory is highly desirable. Experience preparing samples for DNA deep sequencing and demonstrated ability to analyze large datasets are strongly preferred. The successful applicant should have a deep-seated interest in genetics, be an excellent communicator, and have a strong desire to learn about next generation sequencing techologies and data analysis. A strong academic background is highly preferred.

This position is funded by an NIH P51 base operating grant.

Application Deadline:
AUG 28 2019 11:55 PM CST

For full posting and to apply online, please go to:

Contact Information:
Samantha Noordhoek
1220 Capitol Court
Madison, WI 53715

Telephone Number:

Fax Number:


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