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Genetics Research Specialist

Hiring Organization:
Wisconsin National Primate Research Center

Date Posted:

Position Description:
The Wisconsin National Primate Research Center (WNPRC) is one of seven federally supported National Primate Research Centers and the only one in the Midwest. WNPRC's mission is to increase the understanding of basic primate biology and to improve human health and quality of life through research. To accomplish this, the WNPRC helps discover treatments, preventions and cures for human disease; generates new knowledge of primate biology, from the molecular and whole animal levels to the understanding of primate ecosystems; facilitates research progress by providing expertise, resources and training to scientists worldwide; and collects primate information and disseminates to the research community and to the public. Based in the Office of the Vice Chancellor for Research and Graduate Education (OVCRGE) of the University of Wisconsin-Madison (UW-Madison), the WNPRC is committed to diversity both as an end in itself, but also as a valuable means for eliminating health disparities through research. To support this commitment, we encourage applications from candidates who hold these same values of diversity and inclusion.

A position is available in the WNPRC Genetics Services Unit overseen by Dr. David O'Connor at the AIDS Vaccine Research Laboratory. Genetics Services is a research service unit that specializes in fee-for-service high-throughput genotyping of immune loci in nonhuman primates (NHP). Understanding NHP genetics is essential for unlocking the secrets of AIDS immunity, organ transplant tolerance, and susceptibility to infectious disease. The applicant will provide technical assistance to help design experiments and develop improved technologies for understanding the relationship between genetics and disease, while working with other laboratories that provide NHP samples for advanced analyses available only through Genetics Services.

Duties include but are not limited to the following:
- High-throughput isolation of nucleic acids and preparation of templates for DNA sequencing .
- Operate deep DNA sequencing instruments including an Illumina MiSeq and PacBio Sequel .
- Analyze large deep DNA sequencing datasets for Major Histocompatibility Complex (MHC) genotyping as well as additional immunologically important genomic regions such as TRIM5, killer immunoglobulin-like receptors (KIR), and Fc gamma receptors (FCGR) .
- Assist with the preparation of genotyping reports and presentations .
- Evaluate new technology platforms for MHC allele discovery and genotyping .
- Assist with the development and evaluation of new methods for analyzing and curating sequence data for immune gene families such as MHC, TRIM5, KIR and FCGR .
- Assist with administrative components such as purchasing, budget preparation, and project logistics.

Degree and area of specialization:
Bachelor's degree in Genetics, Biology, Microbiology, Immunology, or related field.

BL2+ and radiation certification will be acquired upon hire.

Minimum number of years and type of relevant work experience:
Coursework in a molecular biology or related discipline required. Prior work experience in a research laboratory is highly desirable. Immunogenetics and high throughput DNA sequencing experience strongly preferred.

Additional Information:
A period of evaluation will be required.
A criminal background check will be required.
Please note that successful applicants are responsible for ensuring their eligibility to work in the United States (i.e. a citizen or national of the United States, a lawful permanent resident, a foreign national authorized to work in the United States without need of employer sponsorship) on or before the effective date of appointment.

Application Deadline:
October 15, 2018 at 11:55pm

Please go to and click "Apply Now" to begin the application process. Please submit a cover letter and resume highlighting your experience as it relates to this position, referencing PVL 96178. You will also be required to provide three professional references.

Contact Information:
Samantha Noordhoek
1220 Capitol Court
Madison, WI 53715

Telephone Number:

Fax Number:


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